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Shanghai Proton and Heavy Ion Center

Grade III Specialty · National Particle Therapy Flagship

Shanghai Proton and Heavy Ion Center

Nasopharyngeal cancerProstate cancerBrain tumorLung cancerPancreatic cancer

Established

2015

Beds

220+

Annual Volume

1,200+

Shanghai

China’s first center with both proton and carbon-ion beams; 10,000+ patients treated, 5-year overall survival 70.4% (2026 survival report).

About the Hospital

The Shanghai Proton and Heavy Ion Center (SPHIC, the particle-therapy center of Fudan University Shanghai Cancer Center) is China’s first facility offering both proton and carbon-ion therapy. Since opening in 2015 it has treated over ten thousand patients, ranking among the busiest particle centers worldwide.

Equipped with Siemens pencil-beam scanning, the hospital has built particle-therapy pathways for more than 40 tumor types and systematic data in nasopharyngeal, lung, liver and prostate cancers as well as pediatric tumors, together with mature international patient services and direct-billing insurance arrangements.

Hospital Strengths

01Dual proton and carbon-ion platform

Within one center, physicians select the optimal modality between protons and carbon ions based on lesion location, histology and prior irradiation.

02Internationally published outcomes

Local-control and survival data for key diseases (nasopharyngeal, lung, prostate cancers) are published in international journals at an advanced level.

03One-stop international patient services

A dedicated international department provides English medical records, direct billing with multiple international insurers, accommodation and interpreting support, ensuring a smooth outpatient-based treatment experience.

Key Departments

Head-Neck & CNS TumorsThoracic OncologyAbdominopelvic OncologyPediatric OncologyMedical PhysicsNuclear Medicine

Coordinated Treatment Directions

  1. 01Particle therapy and re-irradiation for head-neck tumors incl. NPC
  2. 02Stereotactic particle therapy for lung cancer
  3. 03Particle therapy for inoperable liver cancer
  4. 04Hypofractionated particle therapy for prostate cancer
  5. 05Proton therapy for pediatric tumors
  6. 06Rare tumors such as skull-base chordoma/chondrosarcoma

Officially Reported Treatment Milestones

Official 10-year report on proton and heavy-ion therapy

2025

By its 10th anniversary, the hospital had treated over 9,300 patients across 40+ tumor types; proton/heavy-ion therapy for locally advanced nasopharyngeal carcinoma achieved internationally leading 5-year overall survival.

World’s first prospective study of heavy-ion therapy for recurrent nasopharyngeal carcinoma

2021

Conducted a prospective clinical study of carbon-ion re-irradiation for recurrent nasopharyngeal carcinoma, significantly reducing severe re-irradiation toxicity; published in leading radiation oncology journals.

Accreditations & Platforms

  • World’s first heavy-ion center treating 1,000+ patients per year
  • Phase II under construction — set to be the world’s largest particle therapy center